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Science / Sat, 31 Oct 2026 Mid-Day

New SPIFFI imaging technique captures live cell dynamics in real-time

Super-resolution microscopy requires hundreds of frames, causing motion blur when capturing fast-moving living cells. A new imaging technique called Spatial Polarisation-Induced Fluorescence Fluctuation Imaging (SPIFFI) overcomes this limitation by leveraging light polarisation during a single camera exposure. This allows scientists to capture fine structures and produce true super-resolution videos of live cellular dynamics in real time, significantly advancing research in biology, neuroscience, modern drug discovery , biomedical, and clinical sciences. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

Super-resolution microscopy requires hundreds of frames, causing motion blur when capturing fast-moving living cells. A new imaging technique called Spatial Polarisation-Induced Fluorescence Fluctuation Imaging (SPIFFI) overcomes this limitation by leveraging light polarisation during a single camera exposure. This allows scientists to capture fine structures and produce true super-resolution videos of live cellular dynamics in real time, significantly advancing research in biology, neuroscience, modern drug discovery , biomedical, and clinical sciences.

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