Oncologists have long wrestled with a conundrum.
Healthy human tissue often carries mutations that can drive cancer, but the tissue itself does not develop tumours.
Clearly, a genetic spark alone is not enough.
At the same time, chronic inflammation from smoking profoundly damages lung tissue long before any definitive cancer-causing mutations even take root.
How then does smoking increase the risk of lung cancer?
Oncologists have long wrestled with a conundrum. Healthy human tissue often carries mutations that can drive cancer, but the tissue itself does not develop tumours. Clearly, a genetic spark alone is not enough. At the same time, chronic inflammation from smoking profoundly damages lung tissue long before any definitive cancer-causing mutations even take root.
How then does smoking increase the risk of lung cancer?