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Health / Mon, 02 Nov 2026 Medical News Today

Does vitamin B12 really help prevent heart disease?

Share on Pinterest There is not sufficient evidence to suggest that vitamin B12 supplementation helps prevent heart disease, a new review concludes. Past research shows that certain vitamins, such as vitamin B12, may help lower heart disease risk. A new review found that taking a vitamin B12 supplement does not consistently prevent major cardiovascular events. The strongest evidence of a potential clinical benefit of vitamin B12 supplementation was in stroke prevention. According to the World Health Organization (WHO), cardiovascular disease is currently the leading cause of death around the world.

Share on Pinterest There is not sufficient evidence to suggest that vitamin B12 supplementation helps prevent heart disease, a new review concludes. fotostorm/ Getty Images

Cardiovascular disease is currently the leading cause of death around the world.

Past research shows that certain vitamins, such as vitamin B12, may help lower heart disease risk.

A new review found that taking a vitamin B12 supplement does not consistently prevent major cardiovascular events.

The strongest evidence of a potential clinical benefit of vitamin B12 supplementation was in stroke prevention.

According to the World Health Organization (WHO), cardiovascular disease is currently the leading cause of death around the world.

Past research shows there are several healthy lifestyle choices people can make to help lower their cardiovascular disease risk, such as following a heart-healthy diet.

“Vitamins play essential roles in many processes that help maintain cardiovascular health, including the normal functioning of blood vessels and the regulation of certain metabolic pathways,” Ameer Awashra, MD, a medical doctor in the Department of Medicine at An-Najah National University in Nablus, Palestine, told Medical News Today.

“Studying these relationships is important because nutritional deficiencies are potentially preventable and treatable. However, we also need to understand whether correcting these deficiencies actually reduces the risk of heart attacks, strokes, and other cardiovascular complications,” Awashra noted.

He is the first author of a new review published in Nutrition Journal, which found that, while vitamin B12 may have certain effects on heart health, taking a supplement does not consistently prevent major cardiovascular events.

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